Lung development

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Contents

Broader Terms

histogenesis

Related Terms

embryology

Scope Note

pulmonary development.

Facts (generated by robot; please edit if you find it inaccurate)

  • Lung development is not necessary for diaphragm development in mice.
  • In addition, morphologic lung development is precocious in the guinea pig, with advanced alveolarization taking place in utero.
  • Lung development is considerably more complex than airway development in Drosophila, as there are more than 15 million airway branches in the human lung, plus a similar number of blood vessels.
  • While the importance of canonical Wnt signalling in lung development is well established, the role of non-canonical Wnt signalling is less clear.
  • Previous studies have established that lung development is severely disrupted in mouse mutants with reduced levels of the proto-oncogene Nmyc, but the precise mechanisms involved have not been explored.

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