Lymphocytic choriomeningitis virus

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LCM virus

Broader Terms

Arenaviridae

Facts (generated by robot; please edit if you find it inaccurate)

  • Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen.
  • Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons.
  • Oldstone 1989 Lymphocytic choriomeningitis virus is perhaps the best known arenavirus.
  • Lymphocytic choriomeningitis virus is not fatal in mice, and signs of illness are unlikely because of the well-adapted host-parasite relationship between the mouse and virus, Dr.
  • The B cell response to lymphocytic choriomeningitis virus is characterized by a CD4(+) T cell-dependent polyclonal hypergammaglobulinemia and delayed formation of virus-specific neutralizing antibodies.

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