Lymphoid neoplasm

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In such cases the lymphoid neoplasm is first diagnosed and the aver-age time from initial diagnosis to the development of the second neoplasm is relatively long, usually more than fifty months2.
The demonstration of mixed lineage in a mature lymphoid neoplasm is unusual and echoes the World Health Organization classification that placed NK-cell and T-cell lymphomas in a mixed group.
13,18 In contrast, the occurrence of a lymphoid neoplasm is rare.
The demonstration of clonality is important when the diagnosis of a lymphoid neoplasm is in doubt and when it is uncertain if a plasma-cell infiltrate is reactive or neoplastic.
We suggest that combination of rituximab with chemotherapy in secondary cold agglutinin disease due to lymphoid neoplasm is better choice than rituximab alone.

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