Lysophospholipase

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Immunogold labeling established that pancreatic lysophospholipase is restricted exclusively to exocrine cells where it occurs only in compartments of the exocytotic pathway.
Lysophospholipase is sourced from Aspergillus niger which is the donor organism for a number of approved enzymes within the Food Standards Code.
We concluded that peak 2 lysophospholipase is regulated by differentiation in HL-60 cells and may play an important role in protec 5a8 ting these cells from the cytolytic effects of the lysophospholipids produced by the activation of phospholipase A2.
The cloned cDNA encoded 564amino acids with a calculated molecular mass of 60,794and showed no sequence similarity to the small form lysophospholipases of rat liver and macrophage, indicating that the large form lysophospholipase is evolutionarily apart from the small form enzyme.
A lysophospholipase is an enzyme that catalyses the hydrolysis of a single fatty acid ester bond in lysoglycerophosphatidates with the formation of glyceryl phosphatidates and a fatty acid (Medical dictionary search engine).

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