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MNNG

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N methyl N' nitro N nitrosoguanidine

Facts

  • MNNG is carcinogenic in all species tested: mouse, rat, hamster, rabbit, and dog.
  • MNNG is a strong alkylating agent resulting in DNA double-strand breaks.
  • t has been well known that MNNG is one of the strong and multipotential carcinogens that have been frequently reported inducing malignant peptic tumors.
  • MNNG is toxic, a severe irritant, a carcinogen,8 and a potent mutagen.
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