Macrophage

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Contents

Used for

foam cell, histiocyte, pericyte

Broader Terms

antigen presenting cell, phagocyte

Narrower Terms

alveolar macrophage

Related Terms

migration inhibition factor, monocyte, scavenger receptor

Scope Note

mononuclear phagocytes found in tissue.

Facts (generated by robot; please edit if you find it inaccurate)

  • Cell membrane Phagocytosis One important main role of macrophage is the removal of necrotic debris and dust in the case of the lungs.
  • Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury.
  • Phosphotyrosine phosphatase activity in the macrophage is enhanced by lipopolysaccharide, tumor necrosis factor alpha, and granulocyte/macrophage-colony stimulating factor: correlation with priming of the respiratory burst.
  • Current medical training includes knowledge of the immune system, and the macrophage is generally recognized as the most important component of the body defense system.
  • Related Collections Lung - transplantation J Thorac Cardiovasc Surg 2003;126:200-207 2003 The American Association for Thoracic Surgery Cardiothoracic transplantation Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury Babu V.

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