Mast cell

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Contents

Used for

granule cell (connective tissue), labrocyte, mastocyte

Broader Terms

connective tissue cell, immune system

Related Terms

chymase, mastocytosis

Scope Note

granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract; like basophils, contain large amounts of histamine and heparin but unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood; mast cells, derived from the bone marrow stem cells, are regulated by stem cell factor.

Facts (generated by robot; please edit if you find it inaccurate)

  • The mast cell is packed with elec- tron dense granules (G) of various sizes and a large nucleus (N).
  • Mast cell is present in the blood smear of a dog with cutaneous neoplasms.
  • Rat mucosal mast cells: the cultured bone marrow-derived mast cell is biochemically and functionally analogous to its counterpart in vivo.
  • The mast cell is a histamine-containing element of the immune system, and mast cell tumors are composed of these cells.
  • 1 Mast cells and basophils Mast cells and basophils play a central role in inflammatory and immediate allergic reactions.
  • mast cell Dictionary mast cell n.
  • Human mast cell progenitors use alpha4-integrin, VCAM-1, and PSGL-1 E-selectin for adhesive interactions with human vascular endothelium under flow conditions.

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