Megaloblastic anemia
From Health Encyclopedia
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Broader Terms
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Narrower Terms
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Related Terms
folate deficiency, vitamin B12 deficiency
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Scope Note
anemias associated with impaired DNA synthesis in bone marrow progenitor cells leading to odd shaped, macrocytic, or dysfunctional erythrocytes; usually caused by B12 or folate deficiency.
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Facts (generated by robot; please edit if you find it inaccurate)
- If the megaloblastic anemia is thought to be caused from a problem in the digestive tract, a barium study of the digestive system may be performed.
- Megaloblastic anemia is the most common cause of macrocytic anemia.
- 1 ICD-9 281 ICD-O: {{{ICDO}}} OMIM {{{OMIM}}} DiseasesDB {{{DiseasesDB}}} MedlinePlus {{{MedlinePlus}}} eMedicine {{{eMedicineSubj}}}/{{{eMedicineTopic}}} Megaloblastic anemia is anemia resulting from a deficiency of vitamin B12 and folic acid.
- Megaloblastic anemia is mainly characterized by larger than normal red blood cells in the blood.
- Megaloblastic anemia is characterized by macro-ovalocytes, in contrast to the round macrocytes usually found in macrocytosis of nonmegaloblastic etiology [1].
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