Megaloblastic anemia

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Contents

Broader Terms

anemia

Narrower Terms

orotic aciduria

Related Terms

folate deficiency, vitamin B12 deficiency

Scope Note

anemias associated with impaired DNA synthesis in bone marrow progenitor cells leading to odd shaped, macrocytic, or dysfunctional erythrocytes; usually caused by B12 or folate deficiency.

Facts (generated by robot; please edit if you find it inaccurate)

  • If the megaloblastic anemia is thought to be caused from a problem in the digestive tract, a barium study of the digestive system may be performed.
  • Megaloblastic anemia is the most common cause of macrocytic anemia.
  • 1 ICD-9 281 ICD-O: {{{ICDO}}} OMIM {{{OMIM}}} DiseasesDB {{{DiseasesDB}}} MedlinePlus {{{MedlinePlus}}} eMedicine {{{eMedicineSubj}}}/{{{eMedicineTopic}}} Megaloblastic anemia is anemia resulting from a deficiency of vitamin B12 and folic acid.
  • Megaloblastic anemia is mainly characterized by larger than normal red blood cells in the blood.
  • Megaloblastic anemia is characterized by macro-ovalocytes, in contrast to the round macrocytes usually found in macrocytosis of nonmegaloblastic etiology [1].

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