Metoclopramide

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Use

antiemetic, phenylamide

Facts (generated by robot; please edit if you find it inaccurate)

  • Another medicine may be used with metoclopramide to prevent side effects that may occur when metoclopramide is used with anticancer medicines.
  • " Metoclopramide is able to cross the blood brain barrier and act on the brain directly to control the sensation of nausea.
  • Additive sedative effects can occur when metoclopramide is given with alcohol, sedatives, hypnotics, narcotics, or tranquilizers.
  • The onset of pharmacological action of metoclopramide is 1 to 3 minutes following an intravenous dose, 10 to 15 minutes following intramuscular administration, and 30 to 60 minutes following an oral dose;pharmacological effects persist for 1 to 2 hours.
  • Metoclopramide normalizes stomach contractions so that food (and bile) can pass in the correct direction.

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