Muscle regeneration
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- Expression of slow myosin heavy chain during muscle regeneration is not always dependent on muscle innervation and calcineurin phosphatase activity.
- Stem cell-mediated muscle regeneration is enhanced by local isoform of insulin-like growth factor 1.
- The importance of controlling light-dark rhythm in muscle regeneration is discussed elsewhere (see pp.
- Furthermore, we have found that the age-related impairment of muscle regeneration is due to a decline in effective Notch signaling, manifested initially as a failure of injured muscle to upregulate the Notch ligand, Delta.
- The functional link between HDAC inhibitors, follistatin, and adult muscle regeneration is especially provocative as an HDAC inhibitor is already being used clinically in humans as an anti-cancer therapeutic.
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