Mushroom toxin
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Facts (generated by robot; please edit if you find it inaccurate)
- One agent derived from a mushroom toxin is MGI-114 (MGI Pharma).
- This typical in-vitro effect of the mushroom toxin is prevented or inhibited by preincubation with disilybin.
- Strongly enhanced toxicity of the mushroom toxin alpha-amanitin by an amatoxin-specific Fab or monoclonal antibody.
- Conformation of the mushroom toxin beta-amanitin in the crystalline state.
- An active fluorescent derivative of the actin-binding mushroom toxin phallacidin has been synthesized.
- The first mutation conferred resistance to the mushroom toxin alpha-amanitin (amar), and the second mutation generated a restriction fragment length polymorphism without altering the protein sequence.
- The control animals were of two groups, one group injected with sterile distilled water and the other injected with phalloidin, a lethal mushroom toxin.
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