Mushroom toxin

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mycotoxin

Facts (generated by robot; please edit if you find it inaccurate)

  • One agent derived from a mushroom toxin is MGI-114 (MGI Pharma).
  • This typical in-vitro effect of the mushroom toxin is prevented or inhibited by preincubation with disilybin.
  • Strongly enhanced toxicity of the mushroom toxin alpha-amanitin by an amatoxin-specific Fab or monoclonal antibody.
  • Conformation of the mushroom toxin beta-amanitin in the crystalline state.
  • An active fluorescent derivative of the actin-binding mushroom toxin phallacidin has been synthesized.
  • The first mutation conferred resistance to the mushroom toxin alpha-amanitin (amar), and the second mutation generated a restriction fragment length polymorphism without altering the protein sequence.
  • The control animals were of two groups, one group injected with sterile distilled water and the other injected with phalloidin, a lethal mushroom toxin.

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