Nephrocalcinosis

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Contents

See for

kidney stone

Broader Terms

calcium disorder, kidney disorder

Related Terms

primary hyperoxaluria, urinary calculi

Scope Note

condition characterized by precipitation of calcium phosphate in the tubules of the kidney, with resultant renal insufficiency.

Facts (generated by robot; please edit if you find it inaccurate)

  • Although microscopic nephrocalcinosis is a theoretical stage between chemical and macroscopic nephrocalcinosis, it seldom is demonstrated as a clinical entity because renal biopsies are not performed in the early stages of metabolic diseases known to lead to the macroscopic stage.
  • Nephrocalcinosis is associated with renal tubular acidosis in children with X-linked hypophosphatemia.
  • Epidemiology Microscopic, or mild, nephrocalcinosis is a common incidental finding at autopsy, but macroscopic nephrocalcinosis is uncommon.
  • Nephrocalcinosis is associated with renal tubular acidosis in children with X-linked hypophosphatemia M Seikaly, R Browne and M Baum Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9063, USA.
  • The pattern of medullary nephrocalcinosis is associated with multiple other entities and is nonspecific.

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