Neurofilament protein

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NFP

Broader Terms

cytoskeletal protein, fibrous protein, nerve /myelin protein

Facts (generated by robot; please edit if you find it inaccurate)

  • Neurofilament protein is differentially distributed in subpopulations of corticocortical projection neurons in the macaque monkey visual pathways.
  • The heavy neurofilament protein is expressed in regenerating adult but not embryonic mammalian optic fibers in vitro.
  • Collectively, these data indicate that the anterograde axonal transport of neurofilament protein is an active process that is dependent, directly or indirectly, on nucleoside triphosphates.
  • Several studies have shown that neurofilament protein is involved in the formation of neuropathological lesions of several neurodegenerative diseases.
  • These data indicate that there was a marked time-dependent accumulation of neu- rofilament protein proximal to the constrictions, which suggests that neurofilament protein is transported antero- gradely in these axons.

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