Neurotensin

Broader Terms

tridecapeptide found in small intestine and brain; induces vasodilation and hypotension and acts as a neurotransmitter in the brain.

What is Neurotensin? Neurotensin is a neuropeptide that exists in the periphery and in the central nervous system.
Neurotensin is a 13-residue peptide transmitter, sharing significant similarity in its 6 C-terminal amino acids with several other neuropeptides, including neuromedin N.
Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells.
Neurotensin is a tridecapeptide originally isolated and characterized from bovine hypothalamus and later, in identical form, from bovine and human intestine.
53, Issue 4, 453-486, December 2001 Neurotensin and Dopamine Interactions Elisabeth B.
Neurotensin stimulates IL-8 expression in human colonic epithelial cells through Rho GTPase-mediated NF-kappa B pathways.
Mesolimbic expression of neurotensin and neurotensin receptor during stress-induced gastric mucosal injury.
Neurotensin-induced bursting of cholinergic basal forebrain neurons promotes gamma and theta activity together with waking and para- doxical sleep.
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