Nociceptin
From Health Encyclopedia
Contents |
[edit]
Broader Terms
[edit]
Related Terms
nociceptor, opioid receptor, pain
[edit]
Scope Note
an opioid peptide that acts as an endogenous agonist of the opioid receptor-like receptor.
[edit]
Facts (generated by robot; please edit if you find it inaccurate)
- Endogenous orphanin FQ / nociceptin is involved in the development of morphine tolerance Shinjae Chung 1, Sigrun Pohl 2, Joanne Zeng 2, Olivier Civelli 2, Rainer K.
- nociceptin is well established in the mouse (Grisel et al.
- Nociceptin is a potent inhibitor of N-type Ca(2+) channels in rat sympathetic ganglion neurons.
- Orphanin FQ/nociceptin is a small protein that Reinscheid and Civelli discovered about four years ago.
- Some feel nociceptin is activated when the body attempts to release opioids over a prolonged period, possibly because too much opioid may cause some unknown problem.
Would you like to discuss or post question about Nociceptin ? Click here !