Nucleic acid hybridization

From Health Encyclopedia

Contents 1 Used for 2 See for 3 Broader Terms 4 Narrower Terms 5 Related Terms 6 Scope Note 7 Facts (generated by robot; please edit if you find it inaccurate)

Used for

annealing of DNA, annealing of RNA

See for

transposon site hybridization, TraSH (transposon site hybridization)

Broader Terms

genetic technique

Narrower Terms

in situ hybridization, northern blotting, nucleic acid denaturation, nucleic acid probe, nucleic acid reconstitution, solution hybridization, southern blotting, subtraction hybridization

Related Terms

chromosome walking, differential display technique, genetic library, microarray technology

Scope Note

"zipping" reaction between complementary DNA or RNA single strands to form a duplex (double stranded) molecule; basis of many techniques for assaying nucleic acid sequence complementarity.

Facts (generated by robot; please edit if you find it inaccurate)

• Nucleic acid hybridization assaysNucleic acid hybridization is a fundamental tool in molecular genetics which takes advantage of the ability of individual single-stranded nucleic acid molecules to form double-stranded molecules (that is, to hybridize to each other).
• OF THE INVENTION Nucleic acid hybridization is an important technique for detecting the presence of particular sequence information.
• DESCRIPTION OF THE RELATED ART The detection of nucleic acid hybridization is the most important technique in the field of nucleic acid chips.
• Introduction Nucleic acid hybridization is a process whereby a DNA or RNA strand forms an ordered series of hydrogen bonds with its complement, creating a duplex structure.
• Nucleic acid hybridization is the formation of sequence-specific, base-paired duplexes from any combination of nucleic acid fragments.

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