Nucleobase

From Health Encyclopedia

Broader Terms

nitrogenous heterocyclic compound

Narrower Terms

adenine, cytosine, guanine, thymine, uracil

Facts (generated by robot; please edit if you find it inaccurate)

• 9 ENZYMOLOGY RNA Nucleobase Is Key To Catalysis Ribozymes use acidic groups for catalysis, just as protein enzymes do AMANDA YARNELL SELF-HELP To cut the phosphate backbone of its RNA substrate (blue), the HDV ribozyme uses an acidic cytosine (red) nucleobase in its active site as a proton donor.
• As well, the pyrrolocytosine nucleobase is expected to be a helix-stabilizing substitution on the basis of increased -stacking interactions as compared to cytosine.
• The order of quenching efficiency is GT, if the nucleobase is oxidized (Seidel et al.
• If a nucleobase is attached to a ribose ring,then it is known asanucleoside.
• These studies, in which a natural nucleoside is substituted with an abasic nucleoside (X), suggest that a nucleobase is absolutely required in C, G, P(3), and P(4) positions for immunostimulatory activity.

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