Nucleoside diphosphate
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- This means that the linkage to a nucleoside diphosphate is decisive for the taken pathway.
- The asymmetrical Np 4 N-ases belong to the nudix protein family, comprising en- zymes that hydrolyze nucleotides in which a nucleoside diphosphate is attached to one of 948 A.
- If the nucleoside diphosphate is UDP, a polymer of U designated poly(U) is formed.
- (b) When the nucleoside diphosphate is trapped at the ATP site, the ternary complex manifests a profound conformational change at the substrate-binding site.
- The biosynthesis of various deoxyhexoses shares a common key intermediate ---4-keto-6-deoxyglucose nucleoside diphosphate or its analogs ---whose formation from glucose nucleoside diphosphate is catalyzed by the NGDH enzyme, an NAD +-dependent oxidoreductase (24, 37).
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