Pantothenate
From Health Encyclopedia
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Use
N acylaminoacid, vitamin B complex
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Facts (generated by robot; please edit if you find it inaccurate)
- Pantothenate is required in Neurospora crassa for assembly of subunit peptides of cytochrome c oxidase and ATPase/ATP synthase.
- Pantothenate is synthesized de novo by plants and micro-organisms; however, animals obtain the vitamin through their diet.
- REFERENCESPantothenate is the product of the ATP-dependent condensation of pantoate and [beta]-alanine and is a direct precursor of coenzyme A.
- Because pantothenic acid is difficult to handle, calcium pantothenate is normally used in diets.
- We show here that pantothenate is taken up by the intracellular parasite via a novel H(+)-coupled transporter, quite different from the Na(+)-coupled transporters that mediate pantothenate uptake into mammalian cells.
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