Pathologic calcification

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Use

calcification, calcium disorder

Facts (generated by robot; please edit if you find it inaccurate)

  • In biomaterials, pathologic calcification is the major cause of bioprosthetic heart valve failure.
  • Although aldehyde pretreatment of Type I collagen sponge implants is a prerequisite for their eventual mineralization, the threshold level of aldehyde-induced cross-linking required to potentiate their maximal pathologic calcification is low.
  • The mechanism of this pathologic calcification is not well defined.
  • Pathologic calcification is part of aging and also may be tissue specific.
  • After reviewing hundreds of radiograms before and after IV EDTA chelation, it is clear that grossly visible pathologic calcification is generally reduced,169 as I have seen on hundreds of before and after radiograms from the practice of Dr.

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