Periaqueductal gray matter

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Contents

Used for

annulus of the aqueduct

See for

central gray matter

Broader Terms

tegmentum

Related Terms

pain

Scope Note

gray matter surrounding the narrow channel through the mesencephalon which connects the third and fourth ventricles of the brain.

Facts (generated by robot; please edit if you find it inaccurate)

  • Dorsolateral periaqueductal gray matter is an area of the brain putatively related to fear and anxiety.
  • Francisco Guimares: One important point in relation to the role of 5-HT in panic and a possible inhibition of periaqueductal gray matter is what happens during a flight reaction.
  • The effect of POEF on central opioid processes is almost certainly location specific as well as receptor specific; very recent data indicate that antinociception produced by morphine injected directly into the periaqueductal gray matter is unaffected by placenta ingestion [4].
  • In other studies, electrical stimulation in periaqueductal gray matter is partially reversed by the narcotic antagonist naloxone.
  • The hypothalamus, especially the preoptic area, plays a crucial role in thermoregulation, and our previous studies showed that the periaqueductal gray matter is important for transmitting efferent signals to thermoregulatory effectors in rats.

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