Phenylbutyrate

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Contents

Broader Terms

butyrate, phenylcarboxylate

Related Terms

antineoplastic

Scope Note

cytostatic, apoptosis inducing agent; effects cell differentiation.

Facts (generated by robot; please edit if you find it inaccurate)

  • Transcriptional upregulation of TGF-alpha by phenylacetate and phenylbutyrate is associated with differentiation of human melanoma cells.
  • Sodium Phenylbutyrate is used for the management of Urea cycle disorders.
  • Sodium phenylbutyrate is an off-white crystalline substance which is soluble in water and has a strong salty taste.
  • Sodium phenylbutyrate is available only with your doctor's prescription in Powder for solution or Tablets (U.
  • On the fifth day phenylbutyrate is initiated at it's maximum tolerated dose, 370 mgs per kilo per day by continuous infusion, which we give for 7 days.

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