Pituitary gonadal axis
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hypothalamic pituitary gonadal axis
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- In addition, since the ovine testis is responsive to endogenous gonadotropic stimulation at this period, it is suggested that the hypothalamic-pituitary-gonadal axis is already operative at this age.
- Since the brain-pituitary-gonadal axis is common to all vertebrates, these discoveries will have wide application in the analysis of reproduction and its social control.
- H ORMONES AND D EVELOPMENT The hypothalamic-pituitary-gonadal axis is active in males and females during three main periods of life: [1] in the midtrimester of the fetal period; [2] early in the neonatal period; and [3] from puberty throughout the reproductive years.
- PATHOPHYSIOLOGY The physiologic regulation of the hypothalamic-pituitary-gonadal axis is shown in Figure 1.
- (d) A widespread endocrine disorder involving the hypothalamic-pituitary-gonadal axis is manifest in women as amenorrhoea and in men as a loss of sexual interest and potency.
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