Polyion
From Health Encyclopedia
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Facts (generated by robot; please edit if you find it inaccurate)
- The cylindrical region near each polyion is an energetically more favorable place for counterions, but at finite temperatures it is entropically unfavorable to localize all counterions in the cylindrical regions leaving the outer regions empty.
- For 2:1 and 2:2 salts, the sign of the free energy is different in the two theories when the polyion is highly charged.
- The strongest complexes are observed for flexible chains, where the polyion is folded around the macroion.
- And, the pHs of the solution are adjusted to the pH level where the protein or polyion is charged sufficiently, by adding aqueous HCl or by using a buffer.
- The degree to which counterions condense around the polyion is dependent on the spacing and distribution of charge along the backbone and thus the conformation of the nucleic acid.
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