Rb gene

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tumor suppressor gene

Facts (generated by robot; please edit if you find it inaccurate)

  • The RB gene is a known tumor suppressor.
  • Loss of heterozygosity of the RB gene is a poor prognostic factor in patients with osteosarcoma.
  • The Rb gene is expressed after birth in those cells that are actively multiplying as they also help form the retina.
  • Top of pageHow does the retinoblastoma gene cause retinoblastoma? The Rb gene is found on chromosome 13.
  • These observations suggest that Rb gene is one of the cellular genes which can be elevated by SV40 directly or indirectly.

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