Recombinase
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- However, little is known about when during hematopoietic development the V(D)J recombinase is first active, nor is it known what elements activate the recombinase in multipotent hematopoietic progenitors.
- 95, Issue 12, 7051-7056, June 9, 1998 Microbiology A site-specific recombinase is required for competitive root colonization by Pseudomonas fluorescens WCS365 Linda C.
- The sequence similarity between RAG1 and Hin recombinase is extended through the DNA-binding region, with a total of 13 residues absolutely conserved in this region.
- The recombinase is made up of two proteins, RAG-1 and RAG-2, which, in conjunction with the non-specific DNA-bending proteins, HMG-1 or HMG-2, recognize the RSS and catalyze site-specific DNA cleavage (see [5,6] for review).
- A recombinase is an enzyme that deletes the DNA fragment located between the two recombinase-specific sites.
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