Serotonin

1 Used for
2 See for
3 Broader Terms
4 Related Terms
5 Scope Note
6 Facts

Used for

5 hydroxytryptamine

See for

5HT, biogenic amine

Broader Terms

neurotransmitter, tryptamine

Related Terms

hydroxyindoleacetate

Scope Note

biochemical messenger and regulator, synthesized from tryptophan; in humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets.

Facts

A hormone found in the brain, platelets, digestive tract, and pineal gland.
Serotonin is synthesized through 2-step process involving a tetrahydrobiopterin-dependent hydroxylation reaction (catalyzed by tryptophan-5-monooxygenase, also called tryptophan hydroxylase) and then a decarboxylation catalyzed by aromatic L-amino acid decarboxylase.
Serotonin is a neurotransmitter present throughout the body.
When nerve cells containing it are activated, serotonin is released.
Serotonin is critical to many brain functions, including the regulation of mood, heart-rate, sleep, appetite, pain, and many others.

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