Tetrodotoxin

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Contents

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Used for

puffer fish toxin, tarichatoxin

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See for

TTX

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Broader Terms

fish poison, marine toxin

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Related Terms

bioterrorism /chemical warfare, sodium channel

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Scope Note

aminoperhydroquinazoline poison found mainly in species of puffer fishes, and some newts; the toxin causes paresthesia and paralysis through interference with neuromuscular conduction.

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Facts (generated by robot; please edit if you find it inaccurate)

  • The metabolic source of tetrodotoxin is uncertain.
  • Ion Channel (from outside cell) Tetrodotoxin is the poison that is produced by the puffer fish and a number of other animals.
  • Food & Drug Administration Bad Bug Book) Tetrodotoxin is the poison that is found within Pufferfish.
  • Tetrodotoxin is also found in the skin of certain frogs and it is the principal poison in venom of blue-ringed octopus.
  • Additionally, tetrodotoxin is similar in structure and mode of action to saxitoxin which is a neurotoxin produced by a marine micro-organism.
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