Transcription factor
From Health Encyclopedia
Contents |
Used for
E protein, genetic effector, gli-3 protein, hepatic nuclear factor 1, hepatocyte nuclear factor, PDZ protein, steroidogenic factor 1, trans acting factor (genetic)
See for
antitermination factor, elongation factor, genetic activator, genetic coactivator, genetic corepressor, genetic inducer, genetic inhibitor, genetic regulatory protein, genetic repressor, initiation factor, regulatory gene product, SF 1, SF1, termination factor, trans acting factor
Broader Terms
DNA binding protein, genetic transcription
Narrower Terms
AP1 protein, cAMP response element binding protein, I kappa B beta, nuclear factor kappa beta, nuclear receptor
Related Terms
Scope Note
diverse group of viral, prokaryotic, and eukaryotic proteins which interact with specific sites on DNA or its associated proteins to initiate or inhibit transcription; not all are DNA binding proteins per se, although that is a BT.
Facts (generated by robot; please edit if you find it inaccurate)
- The AP-2gamma transcription factor is upregulated in advanced-stage ovarian carcinoma.
- A primary antibody specific for an epitope on the bound and active form of the transcription factor is then added followed by subsequent incubation with secondary antibody and Developing Solution to provide an easily quantified, sensitive colorimetric or chemiluminescent readout (See Figure 1).
- 5022 The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression Marie-DominiqueGalibert2, 3, SuzanneCarreira1, 3 and ColinR.
- "When this transcription factor is absent, the hematopoietic (blood) stem cells are more quiescent.
- 2006 European Society for Medical Oncology Promoter methylation of helicase-like transcription factor is associated with the early stages of gastric cancer with family history J.
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