Transcription termination

From Health Encyclopedia

See for

antitermination, antitermination factor, attenuation, termination factor

Broader Terms

genetic transcription

Facts (generated by robot; please edit if you find it inaccurate)

• RNA polymerase II transcription termination is mediated specifically by protein binding to a CCAAT box sequence.
• It is shown here that Rho-dependent transcription termination is highly efficient for each of the individually cloned first and second repeats.
• Transcription termination is preceded by another RNA cleavage, designated pretermination cleavage (PTC) upstream of the elongating polymerase (ref).
• It has been known for quite a long time that transcription termination is somehow intertwined with polyadenylation, but it is still unclear exactly how these two processes influence each other.
• 2) Transcription termination is important, not least because stopping too late will disrupt the regulation of other genes on the same chromosome; stopping prematurely, meanwhile, would produce truncated and therefore defective mRNAs.

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