Transgenic animal
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- For many, the high cost, in both animal lives and money, of making a transgenic animal is not worth the possible benefits.
- For some studies, the selection of an inbred mouse line will be important to the final project for which the transgenic animal is being produced.
- Microinjection of DNA into the pronucleus The pronuclear microinjection method of producing a transgenic animal is based on the introduction of linear DNA sequences into the chromosomes of fertilized eggs.
- What is a transgenic animal? A transgenic animal is one which has been genetically altered to have specific characteristics it otherwise would not have.
- For the purpose of these guidelines, a transgenic animal is defined as an animal that has been experimentally manipulated to integrate recombinant DNA into the genome (chromosomal DNA) of their somatic cells or germ cells (germ cell precursors or cells that produce gametes).
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