Transglutaminase

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protein glutamine gamma glutamyltransferase

Facts (generated by robot; please edit if you find it inaccurate)

• Biochemistry Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity S.
• Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells.
• eduTransglutaminase is a calcium-activated enzyme that crosslinks substrate proteins into insoluble, often filamentous aggregates resistant to proteases.
• Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells, Neuroscience, 102:481-491.
• We found that tissue transglutaminase is overexpressed in atherosclerotic tissue and can alter the composition and stability of extracellular matrices within atherosclerotic tissues.

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