Transneuronal degeneration

From Health Encyclopedia

Broader Terms

neural degeneration

Facts (generated by robot; please edit if you find it inaccurate)

• A biphasic change in ribosomal conformation during transneuronal degeneration is altered by inhibition of mitochondrial, but not cytoplasmic protein synthesis.
• This increase in transneuronal degeneration is temporally associated with a progressive reduction in axonal sprouting following deafferentation during the first 3 postnatal weeks, as described in the companion paper (Friedman and Price, '86).
• Although it is difficult to make compari- son on the basis of our limited material, it seems possible that the initial course of transneuronal degeneration is slower in squirrel monkeys than in macaques .
• The potential for BG lesions to be caused by transneuronal degeneration is raised by the finding that thalamic (subcortical) atrophy is related to injury severity, degree of brain atrophy and the presence of nonthalamic cortical or subcortical lesions, i.
• Transneuronal degeneration did not appear prominent in the LGN of the animal which was allowed to survive for six months, but in the two animals which survived for one year six laminae were clearly present .
• A major problem with the strategy to stimulate ganglion cells is the progressive loss of these cells caused by transneuronal degeneration and reduction in their blood supply.
• Age-dependent cell death in the olfactory cortex: lack of transneuronal degeneration in neonates.
• Transneuronal degeneration in patients with temporal lobe epilepsy: evaluation by MR imaging.
• Retrograde and anterograde transneuronal degeneration, occurs mostly in the very young CNS.

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