Transporter of antigenic peptide

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antigenic peptide transporter

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• They are then, moved from the CytoPlasm to the Rough Endoplasmic Reticulum (RER), by the Transporter of Antigenic Peptide (TAP) protein.
• These peptides are then translocated from the cytoplasm to the rough endoplasmic reticulum (RER) by the transporter of antigenic peptide (TAP) protein.
• However, afterincorporation of b2m, MHC I binds to the soluble lectin calreticulinand is incorporated into the peptide loading complex which alsocontains tapasin, transporter of antigenic peptide (TAP) and ERp57 (amember of the protein disulphide isomerase family).
• Fernandez, Coichester: lntracellular tracing of transporter of antigenic peptide 2 in rat fibroblasts by confocal microscopy.
• The heavy chainb2m dimer, togetherwithassociatedcalreticulinandERp57(adisulphideisomerase), are associated with a larger complex that also contains the transporter of antigenic peptide (TAP) and the transmembrane glycoprotein tapasin.

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