Transthyretin

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retinoid binding protein, thyroid hormone binding protein

Facts (generated by robot; please edit if you find it inaccurate)

  • Transthyretin amyloidogenesis: mechanism and inhibition: 1655 Transthyretin is a 55 kDa homotetrameric protein (Figure 1) that transports L-thyroxine and holo-retinol binding protein in the serum and cerebrospinal fluid.
  • Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro.
  • Transthyretin is not essential for thyroxine to reach the brain and other tissues in transthyretin-null mice.
  • Transthyretin is a tetrameric protein that is the backup transporter of thyroxine and the main transporter of the retinol-binding protein (carries 20% of vitamin A) (14).
  • Transthyretin Transthyretin (also called prealbumin) is a tetrameric human plasma protein known to transport thyroxine and retinol.
  • Characterization of the microheterogeneity of transthyretin in plasma and urine using SELDI-TOF-MS immunoassayFlorian J Schweigert , Kerstin Wirth and Jens Raila Department of Physiology and Pathophysiology, Institute of Nutritional Science, University of Potsdam, A.
  • Low levels of transthyretin in the CSF of depressed patients.

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