WI38 cell
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Scope Note
cell line derived from lung tissue taken from a therapeutically aborted human fetus of about 3 months gestational age; cell morphology is fibroblast-like.
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Facts (generated by robot; please edit if you find it inaccurate)
- Proliferation of the WI38 cell is 12 0 t- 6 z x 0I 0 1 2 3 4 0 1 2 3 4 Time (days) Fig.
- Autocrine stimulation of WI38 cell proliferation in the presence of glucocorticoids.
- In contrast, incubation with Etoposide induces WI38 cell apoptosis and/or senescence in a dose-dependent way, e.
- Donais) Migration of a WI38 cell transfected with alpha-5-GFP.
- However, there was a 2-5-fold increase in the level of expression of the RB1 gene in all the tumor samples compared to the WI38 cell line which was used as control.
- Experimental WI38 cells and SV40-transformed WI38 cells were obtained from the American Type Culture Collection (Rockville, MD, U.
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