I was on 150 mg's daily for my Spinal Tumor Pain. ( 2 and 1/2 years worth.)
It didn't help at all.
It caused Extremely Severe Limb Twitching , whick looked like I was seizing. But I wasn't.
It caused frightening Heart Palpitations that sent me to the ER 5 times in 2 years for an EKG to make sure my heart wasn't exploding , like it felt it was.
I stopped it cold turkey.
Been off it 6 months. I hurt really bad though. No scarey side effects anymore.
I did try Tylenol 3 & 4 and everything in between , working my way to Morphine , Methadone , Fentnyl & Versed.
None of them helped my spinal tumor pain.
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