I was addicted to cocaine for about four years but started taking percocet because it was the closest to the feeling I got with cocaine. However, cocaine is a (an upper)and percocet is an opioid (or a downer). These things are kinda scary to take together. Any drug that contradicts the effects of another drug tends to confuse the body, especially the heart. For example, although cocaine numbs the body, it speeds up the heart. Percocet, if you take enough, will numb the body but slows the heart. This leaves your heart wondering what the heck it's supposed to be doing. Quite a risky combination that will just expect a higher and higher dose each time until the electrical signals in the heart misfire and end up in fibrillation or tachycardia and most likely acute cardiac arrest. But to actually answer your question, once again, percocet is a narcotic which means it is regulated by the federal government. It contains oxycodone and acetaminophen (basically tylenol) which can cause liver damage if taken too often. In laymans terms, the oxycodone binds to receptors in your brain and tells your body it doesn't hurt anymore. The acetaminophen reduces formations of prostaglandins which are basically chemical messengers for the body. So if there's pain, it's really still there but the percocet is telling you it's not. Cocaine does something similar by blocking dopamine receptors in the brain. Dopamine is kind of a precursor to adrenaline and is intended to aide in neurotransmitters (brain messages). By blocking these receptors, dopamine builds up in the brain and thats why you feel all numb and great. So whoever is taking this cocktail is obviously trying to block out a lot of reality and probably can't feel their fingers or toes so hopefully, if we can't get over this and move on with life, just don't drive while you're that intoxicated and try and get off that stuff. It is actually possible, I promise.