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I need to find out more about Tetrahymena.
I would like to know some
general characteristics and observations,
mode of nutrition
and mode of movement?

Please, i would appreciate this.


Tetrahymena are free-living cilia protozoa that can also switch from commensalistic to pathogenic modes of survival. They are common in fresh-water. Tetrahymena species used as model organisms in biomedical research are T. thermophila and T. pyriformis. Tetrahymena ingest a variety of bacterial species. Motility is by cilia, hair like projections on the body.

Since Tetrahymena can be easily cultured in a large quantity in the laboratory, for years it has been a great source for biochemical analysis of important enzymatic activities and for purification of sub-cellular components.

Studies on Tetrahymena have contributed to several scientific milestones:

1. First cell whose division was synchronized , leading to the first insights into the existence of cell cycle control mechanisms.

2. Identification and purification of the first cytoskeleton motor protein, i.e., dynein and determination of its directional activity.

3. Participation in the discovery of lysosomes and peroxisomes.

4. One of earliest molecular descriptions of somatic genome rearrangement.

5. Discovery of the molecular structure of telomeres , telomerase enzyme , the templating role of telomerase RNA and their roles in cellular senescence and chromosome healing.

6. Nobel-prize winning co-discovery of catalytic RNA (ribozyme);

7. Discovery of the function of histone acetylation.

8. Discovery of the roles of RNA interference-like pathway in the heterochromatin formation

9. Demonstration of the physiological roles of the posttranslational modification (i.e. acetylation and glycylation) on tubulins and identification of the enzymes responsible for some of the modifications (glutamylation).