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What is Ciplactin?

Ciplactin is the commercial name for the drug Cyproheptadine which falls under the class of antihistamine drugs. As the name suggests, this class of drugs acts against the action of histamine in the body and thus help fight symptoms like sneezing, runny nose, allergies, sinus inflammation, skin reactions, eczema and more.

Some doctors also prescribe Ciplactin for certain types of headaches and migraines.

Ciplactin side effects

There are certain side effects which require immediate attention such as fainting, having a seizure, confusion, bleeding, ringing in the ears, and an absence of urination. These side effects indicate that your body is having some sort of allergic reaction to the medication and must be looked at immediately.

Other more common side effects include a feeling of drowsiness, dryness of the mouth, alteration of vision, constipation, a feeling of restlessness or excitability (especially in children), and

Can Ciplactin cause weight gain?

One of the effects that Ciplactin (Cyproheptadine) causes is an alteration in the appetite. Some people have reported an increase in hunger while others have reported no change or even a depression. Certain studies have been conducted into this effect taking people suffering from anorexia as subjects and they found that the group taking cyproheptadine gained significantly more weight than the group that was given a placebo.

The exact mechanism behind this effect of the drug is not yet understood. There is also a chance that the sedative effects of the drug that increase drowsiness and lethargy in people could also be responsible for increasing the amount of weight gained, although, that in itself is unlikely to explain the entire weight gain.

Histamine, the chemical agent which this drug blocks has been known to suppress the appetite of some people. Presumably, antihistamine drugs result in an increased appetite because of blocking the release of histamine in the body.

Contraindications for Ciplactin use

People that are suffering from stomach ulcers, have an enlarged prostate, suffer from frequent asthma attacks, or have narrow-angle glaucoma should not be using this drug.  Ciplactin should also not be used to help an adult or a child sleep because that is not its intended effect and can actually have serious consequences.

It is not known whether this drug passes through the breast milk and so women that are breastfeeding their babies should not be taking this drug. The current information states that Ciplactin is not harmful to the developing fetus and so can be taken during pregnancy if the attending gynecologist thinks it is necessary.


Ciplactin is a relatively safe drug that is given commonly to treat allergies, sinus infections, or skin reactions. It also has some well-known side effects including one where weight gain can happen. Studies into the use of Ciplactin for this purpose are being undertaken and have shown positive results, however, a lot more research needs to be undertaken into understanding why it actually happens.

Up until then, it is unlikely that a doctor will prescribe Ciplactin for the express purpose of helping someone gain weight.    

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