I got my first shot back in April 2011. Ive only been on it for almost 2 months and I have already gained 10+ lbs. I cut soda out of my diet and began zumba b/c i had read that this shot could cause weight gain. So far nothing has helped me to maintain nor lose weight. I'm ALWAYS moody now and my boobs hurt constantly. Im always tired and never have a want to do anything anymore. My intimate relationship with my husband has just about decreased to nothing! I constantly get headaches and am bloated 24/7. Since the shot i haven't gotten a period but i have HORRIBLE cramping all the time. I wished i had never gotten this stupid shot! It has been horrible! My advice to anyone is NEVER get this shot!