New study found interesting fact that changes in brain protein could lead to development of Parkinson’s disease which represents degenerative disorder of the central nervous system that often attacks motor skills and speech of the patient. Researchers found that alpha – syneclein protein can be lethal if its amino acid structure lacks a chemical compound called a phosphate. Experts said that this protein may play a crucial role in the development of neurological diseases.

Researchers agree that this finding could lead to the information what causes Parkinson’s disease and it also gives an information what impact does alpha – synuclein have on the brain. During the study they found that by increasing expression of alpha – synuclein protein in brains afflicted with Parkinson’s disease they could provide a gene therapy approach to the disease.

Tests were performed on rat models and researchers used gene transfer to enhance the production of three versions of this protein in particular areas of the brain. They found that the one that stimulated phosphorylation at position 129 of the protein was nontoxic but other versions of protein all caused significant loss of dopamine neurons in the substantia nigra.