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Scientists have long debated whether high homocysteine levels in the blood lead to heart disease and stroke. Homocysteine is an amino acid and a risk factor for the development of arterial disease.

Since it has been proven that raised homocysteine levels in the blood do lead to heart disease and stroke, there is another question whether folic acid, known to reduce homocysteine levels, could aid in reducing heart disease risk.

Folic acid would be a cheap and a simple way of lowering higher homocysteine levels, since it could be taken from foods as well as supplements.

In order to investigate whether raised homocysteine levels caused cardiovascular disease, heart expert Dr David Wald, set out to collect the evidence from different studies.

The first study examined homocysteine levels and the occurrence of heart attacks and strokes in large numbers of people, the second studied included genetics and the third tested the effects of lowering homocysteine levels.

Since folic acid reduces homocysteine concentrations, they logically thought increasing folic acid intake would reduce the risk of heart attacks and strokes.

The U.S. RDA for folate is 400 micrograms per day. We can get folate from fruits and vegetables, grain products, egumes, nuts, and seeds.


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