how much diphenhydramine is an overdose?

i take 150mg every day to help me sleep. that is 3 unisom brand sleep gels. ive been taking this dosage for over 2 years. i will admit there was a few times i felt like was going to die and would be talking to someone and just be so tired that halfway through talking i would forget what i was talking about, but this was almost always around 3 or 4 hours after taking it when i should have been sleeping. today was my day off and i didn't wanna sleep at night so i took them this morning after work and only slept 3 hours. i actually just took them again 15 mins ago. i have an excellent reason for this, i am in the law enforcement field and at first everyone works third shift because officers with higher seniority get the other shifts, and i have a son i take care of by myself, so i must be able to sleep almost on command or else i just do not sleep. without diphenhydramine hcl my life would suck, i would be a walking zombie and most likely have no motivation to get up for work. it has helped me rest when i need to so i can be alert and awake throughout my shift like i should be, however on the flip side i don't think i would EVER take more than 150mg because like i said there was a few times, maybe when i didn't eat breakfast, that it hit harder than other times and btw i only weigh 135 lbs... just thought i would add my input even though this appears to be an old thread.

i know this is like 2 years old but i took 10,000 mgs of benadryl one night and my heart did stop...i spent 4 days in icu and a week on the rehab floor bc it gave me panciatitis...dont take it for a high guys

i have overdosed on nytol twice and i thouh it was going to be the last thing that i do. i dont know how many miligrams they were, it was one a night and i took 16 both times , not with alcohol or anything, just plain water.. and i was weired... my body was out of control. i was shaking or rather twitching...i was talking c**p.. i didnt make sence and i couldnt think clearly/... it was kind of nice to get away from all the other feelings that i experience all the time,.. ,like tinking and imagining things.. i was sort of imagining things when i overdoised but it was different because i was in a state and i couldnt think about it clearly.. i had the normal symptoms like dry mouth ad stuff and whats funny was i couldnt stop my slef from staring.. like my eyes felt so big.. it funny to think about it.

i might do it again to get away from sh*t. it cool. better then street drugs.. and gets the same effect.

there will be days when i work 14 hours without a break. its tough so i take around 40-60 mgs of adderal, then that night i take dyphenhydramine to fall asleep. i take about 100-125mgs of that to give me a chance of getting sleep and being some what rested for the next work day. i've never hallucinated. i have no problems urinating. ive never gotten sick, i just get real tired and fall asleep. i'll wake up a little groggy but it will wear off after i take another dose of adderal. i've also built up a larger tolerance of benadryl (dyphernhydramine) so smaller doses have no effect on me what so ever.

no one on here knows what they're talking about.

I'm 24 and have been taking 300-400 mg every day off and on over the years after battling alcohol addiction. I can tell you that personally the stuff is addictive, especially at such a dosage. It confuses me at times, and it's difficult to stop thinking about negative things. I've only experienced mild hallucinations eg. seeing shadows, being fearful of intruders, aliens etc. However, it dehydrates me greatly and when you take it day after day it makes it hard to swallow. I've also experienced uncomfortable jumps of the heart, almost like skipping a beat. On the wrong days my body reacts harshly which makes it hard to breathe as well and a few times I have felt on the verge of death, only through paranoia I'm sure, nevertheless it was very disconcerting. Being a male it seems to increase sex drive kind of like viagra. I believe it enlarges the prostate. It is a challenge to force myself to concentrate. Oftentimes, my mind wanders and I have bouts of obsessive-compulsive-like behaviours such as making sure I take an even number of sips from my water bottle, constantly adjusting my position in bed, etc. I also believe because of the dehydration factor it has caused my skin to develop wrinkles and age prematurely. I've also had an uncomfortable numbness in my stomach area. I've weened myself down off the stuff a little but it remains a struggle to abstain completely from this stuff given the fact that alcohol looms in the background. I can't stress how WRONG it is to substitute one substance for another. You have to find the underlying factors. I've downloaded some hypnosis and self-help tapes and as corny as they are they do work. I feel as if this substance will kill me if I don't quit. Please people, don't think just because this stuff is over-the-counter that it is safe.

i need to get some sleep tonight cuz i have to wake up early tomorrow and ive been taking sleeping pills for about 8months now. I started out on Tylenol pm which is 25mg? i would take 2 of those every night but about 4 months ago i started doubling the dosage. now i have new ones that are 50mg a pill and take up to three of those a night now and have been for the past 3 weeks. tonight i am really debating on weather or not to take 4 i think ill be fine but i have my doubts. i am 19 6'1 and weigh about 155lbs oh and the first time i took three of those pills i would go out for a smoke and i could a swore i saw a dog down the street playing fetch, and like the smoke would go past me and i thought it was a bug or something. it is all so very hard to walk i stumbled quite a few times on my stairs to my porch. you get very dizzy i think its kinda fun too lol its like being drunk without having to worry about throwing up or waking up with a headache. so ill proabably take four pills so thats 200mg. ill let you guys know on how i did.

I already took 800 mg of diphenhydramine for recreational use and i'm not dead. I don't think you will die with 100 mg lol

Lol this is sooooo old, but I just have to make a reply because people without medical authority or even basic knowledge are spreading misinformation.
Diphenhydramine is a deliriant and a depressant and a sedative. You can take several grams without dieing. You'll probably sleep like 9 hours of of the 100mg dose. I can't imagine any drug possessing a risk of OD at a dose that is 2 time the therapeutic index. I mean its common sense really. If any drug was like that, that dozens of millions of people would die annually. And if such a drug did exist, no doctor would prescribe it to be administered by the patient. That would be far to risky.
Now to the kid on the first page who said he tripped on diphenhydramine by ODing, you are ******. Don't say sh*t if you don't know the chemistry to back it up. 20-30 25mg pills of diphenhydramine in salt form would no cause an OD. Maybe if it was in freebase form, but I doubt it since the bioavailibility of diphenhydramine I believe is around 90% even in salt form, so consuming it in freebase form wouldn't make too much of a difference. That being said, I will explain how the diphenhydramine caused hallucinations. Diphenhydramine binds to 5ht2 serotonin receptors in your brain. At low doses you wont notice it much, you will feel confused a little maybe. If you amp up the dose though, you will start almost dreaming while your awake and feel slow and experience distortions of you audio and visual fields.

***edited by moderator*** ** inappropriate posting**

Guest wrote:

Guest wrote:

Well, I'm 14, but Benadryl is a dangerous substance whatever you do. I don't sleep very well, so I snorted about 250mg of it at one point, and did not fall asleep. I was seeing things and totally tripping on diphenhydramines. I found that it is not wise to ingest too much of the substance in any form, and it surely burns to snort. I would go with 50 to 100mg at most. :]

anyone else suspect a correlation perhaps between "14", "i snorted 250 mg" and unpleasant consequences, such as "burns to snort", "seeing things" and "totally tripping"?

P.S. perhaps the problem with drugs among our youth is merely illiteracy, as last time i checked, tablets are for oral rather than nasal consumption....

He probably crushed them. Although it'd be a funny site to see hime snorting a whole pill.

Wanna know the real long term effect? Try having someone shove a piece of plastic up your Urethra every 4 to 6 hours just so you can pee! That's the situation my wife is now in. After years of diphenhydramine abuse (she thought it was a harmless sleep aid) she is now unable to urinate on her own. :cry: She is off of it now, but the urologist says there's little chance she will ever regain normal function again.

I can verify this person account. I too am a recovering alcoholic (32 y/o) and at first I was taking 500 mg/day. After a couple months I cut down to 200 mg/day and I have been on this does for just over a year. While under the effects of the drug, I too experienced paranoia, OCB, dehydration, increase sex drive, difficulty urinating, and fidgetiness.

It is strangely ironic that I received an email today regarding a reply to this thread as today I have completely run out of my "stock" (I cleaned out my local pharmacy, twice, last time it was discounted) and have been planning on going "cold turkey" this very day.

I took 250mg last Saturday. I'm a 16 year old female I weigh about 120lbs and I'm fine. I tripped really hard. I hallucinated, I was dizzy, and I got really dehydrated. I ended up throwing up involuntary about an hour or so after I took them. Otherwise I probably would have OD'. So just be careful. Not something I would do again.

On january 29 i personally took 200 25mg of benadryl i expierened temporary peralysis in my legs and was out for 17 hrs with a heart rat of 150 for a majority of that time at the time i wieghed 240 and am 5'11"

I used to take benadryl for recreational trips. im very experienced with hallucinations and trips. ive done lsd, 2-cb, mda, mdma etc. me and a good freind of mine have taken 20 one day, than the next take 30, than 40, than 50. we did this for three days going up 10 each day. the first two days were pretty hard trips. smokin cigs that arent their, talkin to people that arent their. but on the third day we both fell asleep before it kicked in and my freinds brother said that i had woken up and was pulling at my shirt and biting at the air. i remember part of it but the thing is, i thought it was a dream but apparently what i thought was a dream was my trip. i couldnt tell reality froma a dream. i remember pulling at my shirt because the white spots were moving and i was trying to pull them off. thats all i remember. but when i woke up and took a shower i was still trippin. i was talking to some black guys while i was naked in the shower. powerful stuff. watch out