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Wysolone, or rather the generic name of the medication, prednisolone, is a synthetic or man-made medication that resembles a naturally occurring corticosteroid hormone that is produced by the adrenal glands of the body.


Prednisolone is used to help manage conditions such as:

  • Blood-related disorders
  • Arthritis
  • Severe allergies
  • Diseases involving the immune system
  • Eye and skin conditions
  • Restrictive and obstructive respiratory illnesses
  • Certain types of cancer

The way prednisolone works is by reducing the body's immune system response to certain types of diseases in order to decrease the symptoms associated with the conditions such as swelling, pain, and allergy-type reactions.

Side Effects

Although the medication is prescribed for indicated medical conditions and a doctor would do so knowing that the benefits outweigh the risks of the drug, side effects can be experienced by the individual using prednisolone.

Many people who use prednisolone do not encounter any serious side effects but if any of the following mentioned ones do occur persistently or worsen, then the individual's doctor or pharmacist should be notified as soon as possible.

Side effects that can be experienced include:

  • Heartburn
  • Dizziness
  • Nausea
  • Headaches
  • Insomnia
  • The development of acne
  • Excessive sweating
  • Changes in menstrual periods

As mentioned, prednisolone acts by lowering the body's immune system response and, therefore, reduces one's ability to fight off infections.

It is very important that patients who are using steroid medications and who start to experience symptoms and signs of an infection such as fevers, chills, coughing, a sore throat, white patches in the mouth, or the development of a thick vaginal discharge should consult with their prescribing doctor as soon as they can.

Prednisolone can also elevate blood sugar levels. This is especially important for patients who are known to be diabetic as elevated glucose levels in the bloodstream can cause diabetic-related complications to develop faster over the long term.

The following are unusual but serious side effects of prednisolone use and the patient's prescribing doctor should be consulted if they are experienced:

  • Unusual generalized fatigue
  • Visual problems
  • Unusual weight gain
  • Swelling of the ankles and/or feet
  • Sustaining bruises easily or bleeding easily
  • Unusual hair growth
  • Mood changes and/or mental health disturbances
  • Swelling or puffiness of the face
  • Muscular pain and/or weakness
  • Slow wound healing
  • Thinning of the skin
  • Bone pain
  • Persistent abdominal pain together with passing black and tarry stools or vomiting coffee-ground-like products.
Immediate medical attention should be sought if a person using prednisolone experiences problems such as convulsions/seizures, chest pain, or bleeding that becomes persistent or excessive or that cannot be controlled.


The following are precautions that are recommended for those patients who are to start using prednisolone as a medication to help manage a specific condition:

  • The prescribing doctor should be made aware of any and all allergies.
  • A comprehensive medical history should be given regarding any other conditions that the patient may have, especially eye, heart, liver, kidney, stomach, blood, mental, and thyroid-related disorders.
  • Alcohol and marijuana use should be restricted or at the very least reduced since the effects of these substances can potentiate those of prednisolone.

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