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Hi I have been on 200mg of sertraline a day for about 11 years now. Apparently I have problem with the receptors in my brain and cannot make or receive sertraline naturally. Years of stress have burnt them out. Anyway I think it took about a month before I really noticed a difference. I had been suicidal and then I became 'normal'. I still get low ocassionally but it is a normal low not an abnormal brain imbalance inducing suicidal low!
I thank God for the tablets as my Specialist said that most people with my condition don't live past 40, they usually end up committing suicide. I am 50 years old and the tablets have given me no problems and only benefits. I hope you find the same applies to you and they help improve your life as they did for me.
Good luck.
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