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I am using Acyclovir all the time, but I had” paused” for over the year. Now I have cold sore, so I put Acyclovir, but after few hours something like a skin rash appeared. Is it possible that I have some reaction on Acyclovir now? Is that some side effect that I am experiencing?

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Well, I guess you have some reaction on it. Maybe cream is out of date or something, did you check? Allergic reaction are possible side effects from Acyclovir, also reaction such as fever, chills, body aches, flu symptoms, swelling, pain, tenderness, or skin changes….
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