I want to know if any if you have had serious reactions to Deposit Medrol injection 80mg for allergic situations like poison ivy and prednisone you are usually given along with it? My life has not been the same.I am angry I was given a shot of something that wasn't explained to me.That was almost three months ago. Injection site still sore.I was told the lady gave it to me in muscle butt area or vein causing the pain. Periods also crazy along with being crazy while on and coming off.All posts appreciated.