Stopping Avonex injections. What effects could I expect?

Hello, Galinhtros.

As you already know, Avonex is a medication used for the treatment of multiple sclerosis (MS). I can offer some general insights into what effects you may expect if you discontinue Avonex without an alternative treatment.

1. Disease Progression: Avonex is prescribed to manage the symptoms and slow down the progression of MS. Stopping the medication may increase the risk of disease activity and progression. MS symptoms, such as fatigue, muscle weakness, balance issues, and cognitive difficulties, may worsen.

2. Relapse Risk: Avonex helps reduce the frequency and severity of relapses in people with relapsing-remitting MS. Discontinuing the medication may increase the likelihood of experiencing relapses or exacerbations of MS symptoms.

3. MRI Findings: Avonex is often used to reduce the formation of new lesions in the brain and spinal cord, as seen on MRI scans. If you stop taking Avonex, there is a possibility that new lesions may appear or existing lesions may become more active.

4. Immune System Changes: Avonex is a disease-modifying therapy that works by modulating the immune system. Stopping the medication may alter immune system activity, potentially leading to changes in the inflammatory response associated with MS.

5. Withdrawal Symptoms: Some individuals may experience withdrawal-like symptoms when discontinuing Avonex. These can include flu-like symptoms, such as fatigue, headache, muscle aches, and fever. It is important to discuss any withdrawal symptoms with your healthcare provider.

It is crucial to emphasize that stopping Avonex or any other MS medication without medical guidance is not recommended. It is odd that your neurologist just stopped it without giving you a replacement. What has he told you?

Hello once again.

In multiple sclerosis (MS), the goal of treatment is typically to reduce inflammation, prevent relapses or flare-ups, and slow down the progression of the disease. If your doctor believes that your MS has stabilized and you're unlikely to have further flare-ups due to a lower inflammatory response, they may consider discontinuing or adjusting your MS treatment. This decision is typically made based on an evaluation of your individual circumstances, including the progression of your MS, the absence of significant new lesions in recent MRI scans, and your overall health.

Stopping MS treatment may have potential benefits, such as reducing the side effects associated with the medications you were taking. However, it's important to weigh the potential benefits against the risks. Without ongoing treatment, there is a possibility that your MS could become active again and lead to flare-ups or further progression of the disease. Additionally, it's important to consider any potential interactions between your MS and other health conditions you have, such as prostate cancer. Your doctor should take into account your entire medical history to make an informed decision.

Considering your recent experiences with prostate cancer, COVID pneumonia, and the loss of your spouse, it's understandable that you may have concerns about stopping MS treatment. It may be helpful to have an open and honest discussion with your doctor about your worries and seek clarification about the reasons behind their recommendation. They can provide you with more specific information about your individual case and help you understand the potential benefits and risks of stopping treatment.

Ultimately, the decision to continue or discontinue MS treatment should be made in consultation with your doctor, considering your overall health, quality of life, and individual circumstances. It may also be helpful to seek a second opinion from another healthcare professional who specializes in MS to ensure you have all the information you need to make an informed choice.