My husband and I have been trying to get pregnant for about one year now. I have PCOS and therefore am taking 7.5 Femara for five days to help me ovulate. This is a high dose and I have noticed that it is making me feel depressed. Luckily it is only for 5 days, but I was wondering if others experienced the same. It does say in the SE it can cause depression, but I was not expecting it since I only need to take it for 5 days.  I am an avid runner and triathlete and I find myself not wanting to get of the couch, which is rare for me. I had taken Clomid as well, but that did not do anything for me. Either way...we are getting closer to taking next steps as I don't want to feel like this anymore. This is not me.